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From81US$ /night
Check-in
13Dec2025Select date
Check-out
14Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4141 Maine Avenue Se, Rochester, Minnesota, United States, 55904
-
Close to Marcus Wehrenberg Cinema 14 IMAX
Perfect
8.5
8.9
/10
4.0
/5

Amenities

Holiday Inn Express Rochester South - Mayo Area provides complimentary parking for guests, making arrival and departure hassle-free. The hotel has a fitness center that operates 24 hours a day, allowing guests to maintain their workout routines. A heated indoor pool invites relaxation and leisure year-round.

Rooms

The hotel offers 96 guest rooms with features such as a work desk and ergonomic chair for business travelers. Each room is equipped with a flat-screen TV for easy entertainment access. Some rooms come with a microwave and refrigerator for added convenience.

Location

Located just minutes from the renowned Mayo Clinic, the hotel is an ideal base for medical travelers. Rochester International Airport is only a short drive away, enhancing accessibility for out-of-town guests. The nearby Apache Mall provides numerous shopping and dining options.

Dining

Holiday Inn Express Rochester South serves a complimentary Express Start breakfast featuring a variety of hot and cold items each morning. Guests can enjoy a selection of coffee and tea available throughout the day. Local restaurants are accessible within a short distance for lunch and dinner options.

Business

The hotel includes a business center equipped with computers and printers for guest use. Meeting rooms are also available for conferences or group gatherings. High-speed internet access throughout the hotel supports all business needs.

Highlights

Location: minutes from Mayo Clinic

Rooms: 96 guest rooms

Dining: complimentary Express Start breakfast

Business: business center available

“The Holiday Inn Express South delivers reliable comfort for Mayo Clinic visits, with free shuttles easing transit; its proximity to local shopping, including the Apache Mall, adds practical appeal. I found the inclusion of a hot breakfast and evening snacks, alongside family-friendly perks like individually controlled room temperatures, particularly thoughtful. For those prioritizing convenience and straightforward value during medical stays, this hotel presents a sensible option.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
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Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
King Suite Jetted Tub
2 persons
1 King-size bed and 1 Sofa bed
Coffee machine
Heating
King Suite Tub Mobility Accessible
2 persons
1 King-size bed and 1 Sofa bed
Coffee machine
Heating
Queen Suite Tub Mobility Accessible
2 persons
2 King Size Beds
Coffee machine
Heating
King Suite Roll Shower Mobility Accessible
2 persons
1 King-size bed and 1 Sofa bed
Shower
Coffee machine
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Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Lift
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre

Services

  • Free airport shuttle
  • Housekeeping
  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Children

  • Cots

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Terrace
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • CD player
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

4141 Maine Avenue Se, Rochester, Minnesota, United States, 55904
Map view
4141 Maine Avenue Se, Rochester, Minnesota, United States, 55904
Nearby
Marcus Wehrenberg Cinema 14 IMAX
450 m
Restaurants
Subway
1.0 km
4576 Maine Avenue SE
Explore Rochester
Local Excitement Around Holiday Inn Express Rochester South
Top Attractions
Activities
Dining
Entertainment
Marcus Wehrenberg Cinema 14 IMAX
11 minutes' walk
IMAX and standard screens showcase the latest films. Special presentations add to a unique cinematic experience.
Shoppes on Maine
15 minutes' walk
A vibrant shopping center featuring local boutiques and popular retail chains, perfect for a leisurely shopping day.
Rochester Market Square
15 minutes' walk
A community hub that often hosts local events and farmers' markets, showcasing regional produce and crafts.
Wood Lake Beach
15 minutes' walk
A scenic spot for picnicking and swimming, featuring trails for walking and biking around the picturesque lake.
Biking at Wood Lake
15 minutes' walk
Biking trails around Wood Lake offer scenic views. Rentals are available at local shops for easy access.
Relaxation at Spas
10 minutes' drive
Nearby spas offer various treatments for relaxation. Appointments recommended for peak times.
Subway
Subway
13 minutes' walk
Casual eatery serving fresh subs and salads. Great for quick bites or takeout, catering to various dietary needs.
Machine Shed Arcade
10 minutes' drive
Rustic American cuisine with hearty portions. Known for comfort foods and a family-friendly atmosphere.
Live Jazz at Tap Room
10 minutes' drive
A lively venue featuring local jazz musicians and themed nights, perfect for an evening out.
Rochester Civic Theatre
10 minutes' drive
Local theater showcasing various performances. Great for families looking to enjoy all-ages shows.
Getting around town
City Centre
Rochester10 min  ·  6.1 km
Airports
Rochester International Airport (RST)13 min  ·  8.2 km
Dodge Center Airport (tob)61 min  ·  40.3 km
Bus
Bus stop3 min  ·  200 m
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in the entire hotel for free.
Breakfast
A full breakfast is served at affordable prices. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of rooms:
126
Former name
Comfort Suites
FAQs
About Holiday Inn Express Rochester South - Mayo Area By Ihg
What are the check-in and check-out times at Holiday Inn Express Rochester South - Mayo Area By Ihg?
Check-in is at 15:00 and check-out is by 11:00.
What distance is Holiday Inn Express Rochester South - Mayo Area By Ihg from Rochester International Airport?
The hotel is 5 km from Rochester International Airport, which is approximately a 10-minute drive.
What amenities does Holiday Inn Express Rochester South - Mayo Area By Ihg provide for guests?
The hotel offers free Wi-Fi, an indoor swimming pool, a fitness center, and hot tub facilities.
What breakfast options are available at Holiday Inn Express Rochester South - Mayo Area By Ihg?
A complimentary hot breakfast is included with the stay.
Is parking available at Holiday Inn Express Rochester South - Mayo Area By Ihg?
Complimentary parking is available on-site without the need for a reservation.
What recreational facilities are available at Holiday Inn Express Rochester South - Mayo Area By Ihg?
Guests can enjoy an indoor heated pool, hot tub, and fitness center.
What nearby attractions can guests visit while staying at Holiday Inn Express Rochester South - Mayo Area By Ihg?
Nearby attractions include Willow Creek Golf Course (3 km), Apache Mall (8 km), and Plummer House (6 km).
Is there a free shuttle service offered by Holiday Inn Express Rochester South - Mayo Area By Ihg?
The hotel offers a complimentary shuttle service to the Mayo Clinic, which is approximately 8 km away.
What room amenities can guests expect at Holiday Inn Express Rochester South - Mayo Area By Ihg?
Rooms feature air conditioning, a flat-screen TV, a coffee maker, and complimentary Wi-Fi.

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